Functional in vitro tension measurements of fascial tissue
a novel modified superfusion approach.
Fascial tissue forms a body wide, continuous three-dimensional viscoelastic matrix of structural support. Fascia is composed of collagenous connective tissue surrounding and interpenetrating skeletal muscle, joints, organs, nerves and vascular beds. Traditionally, fascial tissue was thought to play an important though passive role in the transmission of force for structural support. Recent data, however, has rebutted a mere passive role of fascia in force transmission. Rather Fascial tissue contains contractile elements that actively generate and modulate force within the tissue and are involved in mechano-sensory fine-tuning. Imbalance of this regulatory mechanism causes increased or decreased myofascial tonus, or diminished neuromuscular coordination, which contributes to several musculoskeletal pathologies and pain syndromes (…)
The finding that fascial connective tissue contains contractile elements is suggested to offer new potential treatment options for several pain syndromes
Below the abstract and the complete article of this very interesting research.
While two laboratory techniques are commonly used to assess the tensile properties of muscle tissue, emerging evidence suggests that the fascial components of these tissues also serve an active role in force generation. Hence, we investigated whether these techniques are sensitive for assessment of fascial micromechanics. Methods: Force measurements on dissected fascial tissue were performed either using the classical immersion organ bath or using an improved superfusion approach simulating pulsed pharmacological triggers. Rat deep dorsal fascial strips as well as rat testicular capsule were pharmacologically challenged either with mepyramine or oxytocin. Results: The classical immer- sion technique yielded a lower force response to mepyramine than the superfusion method (median: 367.4 vs. 555.4μN/ mm2). Pause in irrigation before application reduced irregularities during bolus application. The superfusion approach was improved further by the following points: The high sensitivity of the superfusion method to bolus addition was voided by deviation of fluid supply during bolus addition. Conclusion: Although both methods demonstrated pharmacologically induced contractile responses in lumbar fascia samples, the modified superfusion method may improve force registrations of slow contracting fascial tissue and minimize artefacts of fluid application.
Schleip R, Klingler W, Wearing S, Naylor I, Zuegel M, Hoppe K. J Musculoskelet Neuronal Interact 16(3): 256-260 (2016)
SOURCE: International Society of Musculoskeletal and Neuronal Interactions (ISMNI)(http://www.ismni.org)